Thermo Fisher Scientific ERCC2 Monoclonal Antibody (OTI4B11), TrueMAB
ERCC2 단백질을 인식하는 Mouse 단일클론 항체로, Western blot에 최적화되어 있습니다. 인간 시료에 반응하며, 고순도 Affinity chromatography로 정제되었습니다. 액상 형태로 안정적이며, -20°C에서 보관 가능합니다.
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Applications
- Western Blot (WB): 1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4B11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 78–307 of human ERCC2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
XPD is involved in the nucleotide excision repair pathway, which repairs DNA damage. The encoded protein participates in transcription-coupled nucleotide excision repair and is part of the basal transcription factor BTF2/TFIIH complex. It exhibits ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily. Mutations in this gene are associated with xeroderma pigmentosum group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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