Thermo Fisher Scientific AP3B2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Protein corresonding to Human AP3B2. Recombinant protein control fragment (Product #RP-98024). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:AP3B2,uniProtId:Q13367-1,ncbiNodeId:9606,antigenRange:973-1078,antigenLength:1082,antigenImageFileName:PA5-111110_AP3B2_Q13367-1_Rabbit.svg,antigenImageFileNamePDP:PA5-111110_AP3B2_Q13367-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2856520

Product Specific Information

Immunogen sequence: APVFMSENEF KKEQGKLMGM NEITEKLMLP DTCRSDHIVV QKVTATANLG RVPCGTSDEY RFAGRTLTGG SLVLLTLDAR PAGAAQLTVN SEKMVIGTML VKDVIQ

Target Information

The AP3 complex is a heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Unlike the homologous AP3B1, AP3B2-containing AP3 complexes are preferentially targeted to neuronal processes, and mice deficient in AP3B2 displayed compromised synaptic zinc stores.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.