Thermo Fisher Scientific IFN alpha Polyclonal Antibody
인간 IFN-alpha에 특이적인 폴리클로날 항체로, Western blot에 최적화되어 있습니다. 항원 친화 크로마토그래피로 정제되어 순도 95% 이상이며, PBS/glycerol 버퍼에 보관됩니다. 면역 반응 및 바이러스 연구용으로 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:2,000
- View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to residues in Human IFN-alpha |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2803527 |
Product Specific Information
- Purity is >95% by SDS-PAGE.
Target Information
IFN alpha (Interferon alpha) is a Type I interferon belonging to a family of structurally related, species-specific proteins exclusive to vertebrates. The interaction of IFN-alpha with its receptor components activates several signaling pathways involved in the innate immune response against viral infection.
In humans, the IFN alpha gene is located on chromosome 9. Type I interferons consist of 14 different alpha isoforms and single beta, omega, epsilon, and kappa isoforms. Homologous molecules are found in many species, including rats, mice, birds, reptiles, and fish.
IFN alpha is mainly produced by plasmacytoid dendritic cells and plays a key role in antiviral innate immunity and modulation of adaptive immunity.
Diseases associated with IFN alpha dysfunction include Hepatitis C and Hepatitis.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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