Thermo Fisher Scientific GASP1 Monoclonal Antibody (288518)

Applications

Immunohistochemistry (IHC)

• Tested Dilution: 8–25 µg/mL

Product Specifications

Product Specific Information

• In direct ELISAs and Western blots, no cross-reactivity with recombinant human GASP-2 is observed.
• Reconstitute at 0.5 mg/mL in sterile PBS.

Target Information

Growth and differentiation factor-associated serum protein-1 (GASP-1) is a secreted inhibitory TGF-beta binding protein that contains multiple protease inhibitor structural domains. It is expressed primarily in the ovary, testis, and brain, and can act as a potent soluble inhibitor of myostatin and GDF-11, but not Activin A.
The GASP-1 gene encodes a 571 amino acid protein that contains a 29 amino acid secretion signal sequence and multiple identifiable structural features, including:

• WAP domain
• Follistatin/Kazal domain
• Immunoglobulin domain
• Two tandem Kunitz domains
• Netrin domain

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.