Thermo Fisher Scientific GASP1 Monoclonal Antibody (288518)
GASP1 단백질을 인식하는 Mouse IgG2b 단클론 항체로, 인체 시료에 반응합니다. IHC에 사용 가능하며, GASP-2와 교차 반응하지 않습니다. 단백질 A/G로 정제된 동결건조 형태이며, -20°C에서 보관합니다.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: 8–25 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 288518 |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human GASP-1/WFIKKNRP (Leu35–His576) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2606405 |
Product Specific Information
- In direct ELISAs and Western blots, no cross-reactivity with recombinant human GASP-2 is observed.
- Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
Growth and differentiation factor-associated serum protein-1 (GASP-1) is a secreted inhibitory TGF-beta binding protein that contains multiple protease inhibitor structural domains. It is expressed primarily in the ovary, testis, and brain, and can act as a potent soluble inhibitor of myostatin and GDF-11, but not Activin A.
The GASP-1 gene encodes a 571 amino acid protein that contains a 29 amino acid secretion signal sequence and multiple identifiable structural features, including:
- WAP domain
- Follistatin/Kazal domain
- Immunoglobulin domain
- Two tandem Kunitz domains
- Netrin domain
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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