Thermo Fisher Scientific SNAIL Polyclonal Antibody, Biotin
SNAIL 단백질을 인식하는 Biotin-conjugated goat polyclonal antibody. Western blot 및 IHC에 사용 가능. Human 및 Mouse 반응성. 고순도, 0.5 mg/mL 농도. 연구용으로 EMT 및 종양 침윤 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 0.03–0.1 µg/mL
Immunohistochemistry (IHC)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence RKPSDPNRKPNYC (aa 8–19) |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932892 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
Zinc finger protein SNAI1 (SNAIL) is a zinc finger transcriptional repressor that downregulates ectodermal gene expression within the mesoderm and functions in mesoderm and neural crest formation.
SNAI1 is a key factor in tumor invasion through E-cadherin downregulation and induction of epithelial–mesenchymal transition (EMT).
In human breast cancer, SNAI1 and/or SNAI2 (Slug) expression correlates with E-cadherin repression, metastasis, recurrence, and poor prognosis.
Snail 1 protein in the stroma may serve as a potential prognostic marker for colon tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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