Thermo Fisher Scientific IFRD1 Polyclonal Antibody
IFRD1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. 고순도 친화 크로마토그래피 정제. PBS/glycerol buffer에 보관하며 -20°C 저장. 연구용 전용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human IFRD1 (Accession O00458), corresponding to amino acid residues G32–Y82 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850256 |
Product Specific Information
This antibody detects endogenous levels of total IFRD1.
Target Information
Tis7, also known as IFRD1, is a 442 amino acid membrane-associated, non-nuclear intracellular protein belonging to the IFRD family. It acts as a regulatory protein expressed in various tissues and plays an important role in regulating gene activity in proliferative and/or differentiative pathways induced by NGF. Reports suggest that Tis7 may function as an autocrine factor that modulates ligand-induced signaling and supports adaptive responses by stimulating the production of differentiated enterocytes. Tis7 acts as a negative regulator of transcriptional activity, repressing genes involved in myogenesis, muscle maintenance, and regeneration in a histone deacetylase-dependent manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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