Thermo Fisher Scientific PDZD2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human PDZD2. Recombinant protein control fragment (Product #RP-102721). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PDZD2,uniProtId:O15018-1,ncbiNodeId:9606,antigenRange:2257-2356,antigenLength:2839,antigenImageFileName:PA5-57692_PDZD2_O15018-1_Rabbit.svg,antigenImageFileNamePDP:PA5-57692_PDZD2_O15018-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2645362

Product Specific Information

Immunogen sequence: VVPEAKASRG GLPSLANGQG IYSVKPLLDT SRNLPATDEG DIISVQETSC LVTDKIKVTR RHYCYEQNWP HESTSFFSVK QRIKSFENLA NADRPVAKSG

Highest antigen sequence identity to the following orthologs: Mouse - 62%, Rat - 63%.

Target Information

Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signaling. The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.