Thermo Fisher Scientific TAF12 Polyclonal Antibody
TAF12 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:20–1:50 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS(40% glycerol) 완충액에 보관. Human TAF12 단백질에 특이적이며 RNA polymerase II 전사 조절 연구에 적합.
- 판매단위
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TAF12. Recombinant protein control fragment (Product #RP-89333). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2648186 |
Product Specific Information
Immunogen sequence:
NLSNFSSIKP EPASTPPQGS MANSTAVVKI PGTPGAGGRL SPENNQVLTK KKLQDLVREV DPNEQLDEDV EEMLLQIADD FIESVVTAAC QLARHRKSST LEVKDVQLHL ERQWNMWIPG FGSEEIRPYK KACTTEAHKQ RMALIR
- Highest antigen sequence identity to orthologs:
- Mouse: 96%
- Rat: 97%
Target Information
TAF12 is involved in the control of transcription by RNA polymerase II. It participates in the basal transcription machinery, a collection of proteins that assemble with RNA polymerase II into complexes modulated by transactivator proteins binding to cis-regulatory elements near the transcription start site. Some modulators interact directly with the basal complex, while others act as bridging proteins linking transactivators to basal transcription factors. Among these are the TAF proteins, which are tightly associated with TBP in the TFIID complex. Different TAFs mediate the function of distinct transcriptional activators for various gene promoters and RNA polymerases. TAF12 interacts directly with TBP and TAF2I.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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