Thermo Fisher Scientific CDK6 Monoclonal Antibody (75B9)

Applications and Tested Dilution

Product Specifications

Product Specific Information

A suggested positive control for this product is HepG2 cells.

Target Information

CDK6 functions as a cell-cycle initiator protein. This protein is coexpressed and copurified with Cyclin D1, and both are critical regulators of cell cycle progression. The prototype member of this family, p34cdc2, and a related protein cdk2, function late in the cycle, while cdk4 and cdk6 are critically involved in G1 to S progression. CDK6 is essential for cell proliferation within the dentate gyrus of the hippocampus and the cuventricular zone of the lateral ventricles. Mutations in this gene result in microcephaly 12, primary, autosomal recessive (MCPH12).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.