Thermo Fisher Scientific CDK6 Monoclonal Antibody (75B9)
CDK6 단백질을 인식하는 Mouse IgG2b 단일클론 항체로, Western blot, ICC/IF, ELISA 등에 사용 가능. HepG2 세포를 양성 대조군으로 권장하며, 세포 주기 조절 연구에 적합. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:250 |
| Immunocytochemistry (ICC/IF) | 1:250 |
| ELISA | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 75B9 |
| Immunogen | Recombinant human protein purified from E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_1955517 |
Product Specific Information
A suggested positive control for this product is HepG2 cells.
Target Information
CDK6 functions as a cell-cycle initiator protein. This protein is coexpressed and copurified with Cyclin D1, and both are critical regulators of cell cycle progression. The prototype member of this family, p34cdc2, and a related protein cdk2, function late in the cycle, while cdk4 and cdk6 are critically involved in G1 to S progression. CDK6 is essential for cell proliferation within the dentate gyrus of the hippocampus and the cuventricular zone of the lateral ventricles. Mutations in this gene result in microcephaly 12, primary, autosomal recessive (MCPH12).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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