Thermo Fisher Scientific PON1 Monoclonal Antibody (9D3)
PON1 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체(9D3)로, Western blot, IHC, ELISA 등 다양한 연구용 응용에 적합. 마우스/래트 반응성, 항원 친화 크로마토그래피로 정제, 동결건조 형태로 제공되며 -20°C에서 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 0.5–1 µg/mL |
| ELISA (capture) | 1–5 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 9D3 |
| Immunogen | E. coli-derived mouse PON1 recombinant protein (Position: A30–D274) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 4 mg trehalose |
| Contains | 0.05 mg sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2744933 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
The paraoxonase (PON) gene family in humans has three members: PON1, PON2, and PON3, located on chromosome 7q21.3–22.1.
PON1 is synthesized primarily in the liver and secreted into plasma, where it associates with high-density lipoproteins (HDL).
It hydrolyzes active metabolites of several organophosphorus insecticides (e.g., chlorpyrifos oxon, diazoxon) and nerve agents such as sarin, soman, and VX.
PON1 polymorphism has been implicated in neurodegeneration and may be an independent risk factor for Parkinson’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(해당 항원 관련 이미지: MA5-27877_PON1_P52430-1_House_mouse.svg, MA5-27877_PON1_P52430-1_House_mouse_PDP.jpeg)
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