Thermo Fisher Scientific ATG9A Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000–1:10,000

Immunoprecipitation (IP)

• Tested Dilution: 2–10 µg/mg lysate

Product Specifications

Product Specific Information

• Recommended shelf life: 1 year from date of receipt
• Based on 100% sequence identity, this antibody is predicted to react with Rat, Bovine, and Orangutan

Target Information

Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells. It is responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation.
Macroautophagy involves the formation of double-membrane bound autophagosomes that enclose the cytoplasmic constituent targeted for degradation, which then fuse with the lysosome (or vacuole). The resulting autophagic bodies are degraded within the lysosome.
Apg9 plays a direct role in the formation of cytoplasm-to-vacuole targeting and autophagic vesicles, possibly serving as a marker for a specialized compartment essential for these vesicle-mediated targeting pathways.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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