Thermo Fisher Scientific ATF1 Recombinant Rabbit Monoclonal Antibody (23GB4325)
ATF1 단백질을 인식하는 토끼 모노클로날 항체로, Western blot, ICC/IF, Flow cytometry에 적합. HEK293F 발현 시스템에서 생산된 recombinant IgG 형식. 고순도의 affinity chromatography 정제 및 안정한 PBS/glycerol buffer 보존. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunocytochemistry (ICC/IF) | 1:1,000 |
| Flow Cytometry (Flow) | 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB4325 |
| Immunogen | A synthesized peptide derived from human ATF1 (200–271AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
The ATF1 gene encodes an activating transcription factor belonging to the ATF subfamily and bZIP (basic-region leucine zipper) family. It regulates downstream target genes involved in cellular growth, survival, and other processes. Phosphorylation at serine 63 by various kinases enhances its transactivation and transcriptional activities, contributing to cell transformation. Gene fusion events involving FUS (chromosome 16) or EWSR1 (chromosome 22) can generate chimeric proteins associated with angiomatoid fibrous histiocytoma and clear cell sarcoma. A pseudogene is located on chromosome 6.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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