Thermo Fisher Scientific IDH1 Monoclonal Antibody (OTI2H9), DyLight 488, TrueMAB
IDH1 (mutant R132H)에 특이적인 DyLight 488 결합 단클론 항체로, Flow Cytometry에 적합합니다. 인간 시료 반응성이 있으며, 고순도의 Affinity chromatography로 정제되었습니다. 안정한 PBS/BSA/glycerol buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
- Flow Cytometry (Flow): 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2H9 |
| Immunogen | Full-length protein expressed in 293T cell transfected with human IDH1 expression vector (IDH1 mutant R132H, UniProt ID: O75874-1, antigen range: 1–414) |
| Conjugate | DyLight™ 488 |
| Excitation / Emission Max | 492 / 519 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 0.1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
Isocitrate dehydrogenases (IDH) catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes are divided into NAD(+)-dependent and NADP(+)-dependent subclasses.
IDH1 is a cytoplasmic and peroxisomal NADP(+)-dependent enzyme that plays a key role in NADPH production. It contains a PTS-1 peroxisomal targeting signal and contributes to intraperoxisomal redox reactions.
This antibody specifically recognizes IDH1 (mutant R132H).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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