Thermo Fisher Scientific CEP170 Polyclonal Antibody
Rabbit polyclonal antibody targeting human CEP170 protein. Validated for ICC/IF applications with 1:100–1:500 dilution. Supplied as liquid, 0.25 mg/mL, purified by antigen affinity chromatography. Recommended storage at 4°C. For research use only.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1534 and the C-terminus (residue 1584) of human centrosomal protein 170 kDa |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4 °C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Bovine, Rabbit, and Chimpanzee.
Target Information
The CEP170 gene encodes a centrosomal protein that functions as part of the microtubule-organizing center in animal cells. During interphase, it localizes to the sub-distal appendages of mature centrioles, aiding in centrosome organization. During mitosis, it associates with spindle microtubules near centrosomes. The protein interacts with and is phosphorylated by polo-like kinase 1, contributing to microtubule organization and cell morphology. The human genome includes a putative pseudogene, and several alternatively spliced transcript variants have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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