Thermo Fisher Scientific TNFRSF14 Monoclonal Antibody (OTI1F12), TrueMAB
인간 TNFRSF14 단백질(아미노산 39–283)에 특이적인 마우스 모노클로날 항체로, Western blot에 적합합니다. 액상 형태이며 1 mg/mL 농도, PBS/BSA/글리세롤 버퍼에 보관됩니다. 면역 반응 및 HSV 진입 연구용으로 활용됩니다.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 39–283 of human TNFRSF14 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
TNFRSF14 is a member of the TNF-receptor superfamily and acts as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV glycoprotein D (gD) to TNFRSF14 is involved in viral entry. The cytoplasmic region interacts with TRAF family members, mediating signal transduction pathways that activate immune responses. TNFRSF14 activation in T cells promotes proliferation and cytokine production, enhancing inflammation and CTL-mediated tumor immunity. Multiple alternatively spliced transcript variants exist, though some full-length forms remain undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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