Thermo Fisher Scientific HP1 beta Polyclonal Antibody
Human HP1 beta/CBX1 단백질에 특이적인 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF, IP 등 다양한 응용 가능. 고순도 Protein A/Antigen affinity 정제. 액상 형태로 1 mg/mL 농도, 안정적인 저장 및 운송 조건 제공.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:300–1:10,000 |
| Immunoprecipitation (IP) | 5–10 µL/mg of lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the center region of the Human HP1 beta/CBX1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7 |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2788701 |
Product Specific Information
This antibody has specificity for Human HP1 Beta/CBX1.
Target Information
This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. It contains an N-terminal chromodomain that binds to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain responsible for homodimerization and interaction with various chromatin-associated nonhistone proteins. This protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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