Thermo Fisher Scientific PREP Polyclonal Antibody
Thermo Fisher Scientific의 PREP Polyclonal Antibody는 인간, 마우스, 랫트 시료에 반응하며 Western blot, IHC, ICC/IF에 적합합니다. Rabbit IgG 폴리클로날 항체로, 합성 펩타이드 항원을 기반으로 제작되었습니다. 액상 형태이며 -20°C에서 보관합니다.
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PREP (Accession P48147), corresponding to amino acid residues L168–D218. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2900433 |
Product Specific Information
This antibody detects endogenous levels of total Prolyl Endopeptidase.
Target Information
p33cdk2 associates with cyclin A in human cells. Kinase activity associated with cyclin A-cdc2 is found only in G2-phase. Cdk2 also complexes with cyclins E, D1, and D3. Cyclin E-cdk2 kinase is active in the G1- and S-phases of the cell cycle and is important (as does cyclin A-cdk2) for the progression from G1-to S-phase. The levels of cyclin A-cdk2 are maximal at the G1/S transition, and both cdk2 and cyclin A are found associated with DNA in the initiation complex during replication. Rb protein acts as a substrate for cdk2-cyclin E and/or cdk2-cyclin A in vivo. Cdk2 is activated and specifically localized to the nucleus during late G1-, S-, and G2-phase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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