Thermo Fisher Scientific RELA Monoclonal Antibody (8G3)
인간 RELA(NF-κB p65) 단백질을 인식하는 mouse monoclonal antibody(클론 8G3). Western blot 및 ELISA에 적합하며, 비결합형 액상 형태로 제공. -20°C 보관, 방부제 무첨가. 연구용 전용 시약.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 8G3 |
| Immunogen | RELA (NP_068810, 432–505 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
GEGTLSEALL QLQFDDEDLG ALLGNSTDPA VFTDLASVDN SEFQQLLNQG IPVAPHTTEP MLMEYPEAIT RLVT
Target Information
Nuclear factor kB p65 (NF-κB p65) is encoded by the RELA gene and is located on chromosome 11 in humans.
NF-κB p65, also known as RelA, belongs to the Rel family of proteins and forms a heterodimer with p50 or p52 subunits.
Upon TNF-α receptor activation, IKK phosphorylates IκB, leading to its proteasomal degradation. RELA plays a key role in transcription of the immunoglobulin k (kappa) gene in mature B-lymphoid cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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