Thermo Fisher Scientific IL-5 Monoclonal Antibody (299298)
IL-5 단클론 항체로 랫트 IL-5를 특이적으로 인식하며, 중화 및 면역형광(ICC/IF) 실험에 적합합니다. Protein A/G로 정제된 무보존제 제형으로, -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 8–25 µg/mL
Neutralization (Neu)
- Tested Dilution: 0.2–1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 299298 |
| Immunogen | Sf 21-derived recombinant rat IL-5 (Met20–Val132) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2608058 |
Product Specific Information
Reconstitute at 0.5 mg/mL in sterile PBS.
Endotoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
Target Information
IL-5 is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. It is a major regulator of eosinopoiesis, eosinophil maturation, and activation. Elevated IL-5 levels are associated with asthma and hypereosinophilic syndromes.
The IL-5 receptor is a heterodimer whose beta subunit is shared with the receptors for IL-3 and CSF2 (GM-CSF). IL-5, along with IL-4, IL-13, and CSF2, forms a cytokine gene cluster on chromosome 5 (5q31), regulated by long-range elements over 120 kilobases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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