Thermo Fisher Scientific MRPS31 Polyclonal Antibody
Rabbit polyclonal antibody targeting human MRPS31. Validated for WB and ICC/IF. Detects endogenous MRPS31 protein. Supplied as liquid, 1 mg/mL, affinity purified, stored at -20°C. For research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MRPS31 (Accession Q92665), corresponding to amino acid residues Y142–R192 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852853 |
Product Specific Information
Antibody detects endogenous levels of total MRPS31.
Target Information
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and are involved in mitochondrial protein synthesis. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit, with approximately 75% protein to rRNA composition—opposite to prokaryotic ribosomes. Unlike prokaryotic ribosomes, mammalian mitoribosomes lack a 5S rRNA. The proteins comprising the mitoribosome vary greatly among species, hindering recognition by sequence homology. The 28S subunit may play a key role in translation initiation. The MRPS31 gene encodes a 28S subunit protein and has been associated with type 1 diabetes, though its role in disease etiology remains unclear. Pseudogenes are found on chromosomes 3 and 13.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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