Thermo Fisher Scientific OPRM1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide comprising residues N(386) H Q L E N L E A E T A P L P(400) of human, mouse and rat MOR-1. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:OPRM1,uniProtId:P35372-1,ncbiNodeId:9606,antigenRange:386-400|387-400,antigenLength:400,antigenImageFileName:PA1-4561_OPRM1_P35372-1_Rabbit.svg,antigenImageFileNamePDP:PA1-4561_OPRM1_P35372-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2156365

Product Specific Information

PA1-4561 detects mu Opioid Receptor from human, mouse, and rat samples.

PA1-4561 has been successfully used in Western blotting applications. This antibody will detect a dominant band of ~46 kDa representing the monomer form of MOR-1, and may also detect dimmers or trimers as heterodimerization and homodimerization is common

The PA1-4561 immunogen is a synthetic peptide comprising residues N(386) H Q L E N L E A E T A P L P(400) of human, mouse and rat MOR-1.

Target Information

The OPRM1 gene encodes the mu opioid receptor, which is the primary site of action for the most commonly used opioids, including morphine, heroin, fentanyl, and methadone. It is also the primary receptor for endogenous opioid peptides beta-endorphin and the enkephalins. The OPRM1 receptor is a membrane of the G protein-coupled receptor family. There are at least 3 types of opioid receptors, mu, kappa, and delta, each with a distinct pharmacologic profile.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.