Thermo Fisher Scientific CBX6 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

2.5 µg/mL

-

Immunohistochemistry (IHC)

5 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide directed towards the N-terminal of human CBX6 (aa 11-60). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CBX6,uniProtId:O95503-1,ncbiNodeId:9606,antigenRange:11-60,antigenLength:412,antigenImageFileName:PA5-41549_CBX6_O95503-1_Rabbit.svg,antigenImageFileNamePDP:PA5-41549_CBX6_O95503-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS with 2% sucrose

Contains

0.09% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2609905

Product Specific Information

Peptide sequence: FAAESIIKRR IRKGRIEYLV KWKGWAIKYS TWEPEENILD SRLIAAFEQK

Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Target Information

Polycomb group (PcG) proteins form multiprotein complexes that regulate expression patterns of developmental and cell proliferation genes. CBX6 (chromobox protein homolog 6) is a 412 amino acid protein that is a component of the chromatin-associated PcG complex. Through interaction with PcG, CBX6 modifies chromatin and maintains the transcriptionally repressive state of genes. Members of the chromobox domain protein family are characterized by the presence of a 37 amino acid chromobox (CHRromatin Organization MOdifier) domain. This domain plays a mechanistic role in targeting chromodomain proteins to specific regions of the nucleus.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.