Thermo Fisher Scientific SAFB Polyclonal Antibody
SAFB 단백질을 인식하는 Rabbit Polyclonal Antibody로 인간, 마우스, 랫트 반응성이 있음. WB, IHC, ICC/IF, ELISA 등 다양한 응용 가능. 고순도 Affinity Chromatography 정제, 액상 형태로 -20°C 보관. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–200 of human SAFB (NP_0011882671) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.14 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2901741 |
Product Specific Information
- Positive Samples: U-87MG, DU145, NIH/3T3, Mouse brain, Mouse lung, Rat brain
- Immunogen sequence:
MAETLSGLGD SGAAGAAALS SASSETGTRR LSDLRVIDLR AELRKRNVDS SGNKSVLMER LKKAIEDEGG NPDEIEITSE GNKKTSKRSS KGRKPEEEGV EDNGLEENSG DGQEDVETSL ENLQDIDIMD ISVLDEAEID NGSVADCVED DDADNLQESL SDSRELVEGE MKELPEQLQE HAIEDKETIN NLDTSSSDFT
Target Information
This gene encodes a DNA-binding protein with high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). It is involved in attaching chromatin loops to the nuclear matrix and may act as a molecular base for assembling a transcriptosome complex near actively transcribed genes. Additionally, it regulates heat shock protein 27 transcription, functions as an estrogen receptor co-repressor, and is a candidate for breast tumorigenesis. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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