Thermo Fisher Scientific 53BP2 Polyclonal Antibody
53BP2 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody. Western blot에 사용 가능하며 인간과 생쥐 시료에 반응. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공. 세포 성장 및 apoptosis 연구용.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TP53BP2 (Accession Q13625), corresponding to amino acid residues G672–R722 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899339 |
Product Specific Information
Antibody detects endogenous levels of total ASPP2.
Target Information
Regulator that plays a central role in the regulation of apoptosis and cell growth via its interactions.
Regulates TP53 by enhancing its DNA binding and transactivation function on the promoters of proapoptotic genes in vivo.
Inhibits APPBP1 conjugation of NEDD8 to CUL1, thereby decreasing APPBP1-induced apoptosis.
Impacts cell cycle progression at G2/M phase.
Its apoptosis-stimulating activity is inhibited by interaction with DDX42.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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