Thermo Fisher Scientific MECR Polyclonal Antibody
Thermo Fisher Scientific의 MECR Polyclonal Antibody는 인간, 마우스, 랫트 반응성을 가지며 Western blot 분석에 적합합니다. 항원 친화 크로마토그래피로 정제된 액상 항체로, 1 mg/mL 농도이며 PBS에 0.02% sodium azide가 포함되어 있습니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 15 amino acid peptide near the carboxy terminus of human MECR |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at –20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551842 |
Product Specific Information
- A suggested positive control is human brain tissue lysate.
- PA5-34490 can be used with blocking peptide PEP-1532.
Target Information
The mitochondrial trans-2-enoyl-CoA reductase (MECR), initially identified as nuclear receptor-binding factor 1 (NRBF1), interacts with various nuclear hormone receptors in the presence of their ligands. MECR is part of the mitochondrial fatty acid synthesis (FAS II) system and catalyzes the NADPH-dependent reduction of 2-enoyl thioesters, generating saturated acyl groups. Overexpression of this gene in transgenic mice can lead to cardiac abnormalities, suggesting that inappropriate expression of FAS II genes may result in hereditary cardiomyopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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