Thermo Fisher Scientific HK2 Monoclonal Antibody (4H1)

Thermo Fisher Scientific HK2 Monoclonal Antibody (4H1)

Applications and Tested Dilution

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
IVKEVCTVVA RRAAQLCGAG MAAVVDRIRE NRGLDALKVT VGVDGTLYKL HPHFAKVMHE TVKDLAPKCD VSFLQSEDGS GKGAALITAV ACRIREAGQR

Target Information

In vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III, and IV.
Hexokinase activity is involved in the first step in several metabolic pathways including phosphorylation of glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway.
Hexokinase is an allosteric enzyme inhibited by its product GLC-6-P.
Hexokinase 2 is the predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle.
Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.

Usage Notice

For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.

제품 이미지

(이미지 없음)