Thermo Fisher Scientific Phospho-TOB1 (Ser164) Polyclonal Antibody
인산화된 TOB1(Ser164) 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(Paraffin)에서 검증됨. 인간, 마우스, 랫트 반응성. 고순도 Affinity chromatography 정제, 1 mg/mL 농도. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence around phosphorylation site of Serine 164 (A-V-S(p)-P-T) derived from Human TOB1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2554388 |
Product Specific Information
- Suggested positive control for Western blot: HeLa or A549 cells
- Suggested positive control for IHC: Human brain tissue
Target Information
This gene encodes a member of the tob/btg1 family of anti-proliferative proteins that regulate cell growth. When exogenously expressed, this protein suppresses cell growth in tissue culture. It is phosphorylated by a serine/threonine kinase, 90 kDa ribosomal S6 kinase. Interaction with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins. It interacts with mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance DNA binding activity, inhibiting interleukin 2 transcription in T cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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