Thermo Fisher Scientific CSK Monoclonal Antibody (CSK-04)
CSK 단백질을 인식하는 Mouse Monoclonal Antibody로 Western blot, ICC/IF, IP에 사용 가능. Human 및 Mouse 시료 반응. Recombinant CSK(aa 330-450) 면역원으로 제작. Protein A 정제, 1 mg/mL 농도, PBS/NaN3 용액. 연구용으로만 사용.
- 카탈로그번호
- MA134816
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:250–1:300 |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CSK-04 |
| Immunogen | Recombinant fragment corresponding to amino acids 330–450 of Human CSK (VSDFGLTKEAS STQDTGKLPV KWTAPEALRE KKFSTKSDVW SFGILLWEIY SFGRVPYPRI PLKDVVPRVE KGYKMDAPDG CPPAVYEVMK NCWHLDAAMR PSFLQLREQL EHIKTHELHL) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS |
| Contains | 15 mM sodium azide |
| Storage conditions | 4 °C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1955628 |
Product Specific Information
MA1-34816 detects CSK from human and mouse samples.
Target Information
CSK (C-terminal Src kinase) is a tyrosine kinase that downregulates SRC oncoprotein activity via phosphorylation of its C-terminal region. It may function as an antioncogene, regulating cell growth, differentiation, migration, and immune responses. CSK phosphorylates tyrosine residues in the C-terminal tails of Src-family kinases such as LCK, SRC, HCK, FYN, LYN, and YES1. It is ubiquitously expressed (~50 kDa) in the cytosol, with a fraction localized to lipid rafts through interaction with PAG (Csk-binding protein).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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