Thermo Fisher Scientific Cdc42EP4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human Cdc42EP4. Recombinant protein control fragment (Product #RP-93478). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CDC42EP4,uniProtId:Q9H3Q1-1,ncbiNodeId:9606,antigenRange:35-134,antigenLength:356,antigenImageFileName:PA5-54769_CDC42EP4_Q9H3Q1-1_Rabbit.svg,antigenImageFileNamePDP:PA5-54769_CDC42EP4_Q9H3Q1-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.4 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2639566

Product Specific Information

Immunogen sequence: RHTMHVGRAG DAFGDTSFLN SKAGEPDGES LDEQPSSSSS KRSLLSRKFR GSKRSQSVTR GEREQRDMLG SLRDSALFVK NAMSLPQLNE KEAAEKGTSK

Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 87%.

Target Information

The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.