Thermo Fisher Scientific CD45RO Monoclonal Antibody (UCHL1), PerCP
인간 CD45RO 항원을 인식하는 UCHL1 클론 단일클론 항체로, PerCP 형광 표지되어 Flow Cytometry에 적합. 488 nm에서 여기되어 R-PE 채널 간 간섭이 최소. 면역세포 표지 및 신호전달 연구에 활용 가능.
- 카탈로그번호
- MHCD45RO31
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific CD45RO Monoclonal Antibody (UCHL1), PerCP
Applications
- Flow Cytometry (Assay-dependent)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UCHL1 |
| Immunogen | Human CD45RO |
| Conjugate | PerCP |
| Excitation / Emission Max | 482 / 675 nm |
| Form | Liquid |
| Purification | Purified |
| Storage Buffer | PBS with 4 mg/mL BSA, sucrose |
| Contains | 0.1% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10376021 |
Additional Formats
Product Specific Information
PerCP conjugates are excited by the 488 nm line of the argon-ion laser and have a large Stokes shift, providing minimal spectral overlap into the R-PE (phycoerythrin) channel.
Target Information
CD45RO (UCHL1, ubiquitin carboxyl terminal esterase L1) is the shortest isoform of a receptor-type protein tyrosine phosphatase, CD45 glycoprotein.
CD45 is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases.
It promotes cell survival by modulating integrin-mediated signal transduction and is involved in DNA fragmentation during apoptosis.
CD45RO is expressed on macrophages, CD8+ T cells, activated T cells, and myeloma cells.
CD45 isoforms differ in extracellular domains and their ability to translocate into glycosphingolipid-enriched membrane domains; expression depends on cell type and physiological state.
Note
Analyte Specific Reagent
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