Thermo Fisher Scientific KLF3 Polyclonal Antibody
KLF3 단백질을 인식하는 Thermo Fisher Scientific의 염소 폴리클로날 항체입니다. Western blot, ICC/IF, Flow Cytometry, ChIP 등 다양한 응용에 적합합니다. Human에 반응하며, 서열 상 유사성으로 다른 종에도 예측 반응합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–3 µg/mL | View 3 publications |
| Immunocytochemistry (ICC/IF) | 10 µg/mL | - |
| Flow Cytometry (Flow) | 10 µg/mL | - |
| ChIP assay (ChIP) | - | View 4 publications |
| Gel Shift (GS) | - | View 3 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published species | Human, Mouse, Non-human primate |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (LMFDPVPVKQEAMD) corresponding to the N-terminus amino acids of KLF3 (aa 2–16). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_10982084 |
Product Specific Information
This antibody is predicted to react with bovine, canine, mouse, porcine, and rat based on sequence homology.
It has been tested in Peptide ELISA with an antibody detection limit dilution of 1:32,000.
Target Information
Krueppel-like factors (KLFs) are a family of evolutionarily conserved zinc finger-containing transcription factors involved in cell growth, proliferation, differentiation, and embryogenesis.
Members of the Sp1-like/KLF family can act as activators or repressors depending on promoter binding and coregulator interactions.
KLF6 (also known as Zf9 or CPBP) and KLF3 are Kruppel-like zinc finger transcription factors. KLF6 is induced during hepatic stellate cell activation and transactivates collagen I promoter-driven reporter genes, suggesting a role in tissue injury response.
KLF3 may play a role in hematopoiesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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