Thermo Fisher Scientific PPP2R1B Polyclonal Antibody
PPP2R1B 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot, IHC, ICC/IF에 사용 가능. 인간 시료에 반응하며, 항원 친화 크로마토그래피로 정제됨. 안정적인 액상 형태로 4°C 또는 -20°C 보관.
- 카탈로그번호
- PA553877
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PPP2R1B. Recombinant protein control fragment (Product # RP-92510) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2645883 |
Product Specific Information
Immunogen sequence:
NALQGEVKPV LQKLGQDEDM DVKYFAQEAI SVVAQRLRKL EFPVKDSGEP
SVPRADKNHF PRPTVPGEDM GKGPVYQLRG DTRDTLAQLG IAELVHFSQS TD- Highest antigen sequence identity to the following orthologs:
- Mouse: 79%
- Rat: 32%
Target Information
In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis, and apoptosis. A group of proteins intimately involved in this process are the protein phosphatases.
The protein phosphatase (PP) holoenzyme is generally a trimeric complex composed of a regulatory subunit, a variable subunit, and a catalytic subunit. Four major families of protein phosphatase catalytic subunits have been identified: PP1, PP2A, PP2B (calcineurin), and PP2C. An additional subunit, PPX (also known as PP4), is a putative member of a novel PP family.
The PP2A family comprises subfamily members PP2A alpha and PP2A beta. The PP2A catalytic subunit associates with a variety of regulatory subunits, including PP2A-A alpha and -A beta, PP2A-B alpha and -B beta, PP2A-C alpha and -C beta, and PP2A-B56 alpha and -B56 beta.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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