Thermo Fisher Scientific ABCA6 Monoclonal Antibody (2F1)
ABCA6 단백질을 표적으로 하는 Mouse IgG1 단일클론 항체. Western blot 및 ELISA 검증 완료. 인간 시료에 반응하며, PBS 용액 형태로 제공. Affinity chromatography로 정제되어 연구용으로 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
- Publications: 없음
ELISA
- Tested Dilution: 3 ng/mL
- Publications: 없음
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2F1 |
| Immunogen | ABCA6 (NP_525023, 53 a.a. ~149 a.a.) partial recombinant protein with GST tag (MW of GST tag = 26 KDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
NVQFPGMAPQ NLGRVDKFNS SSLMVVYTPI SNLTQQIMNK TALAPLLKGT SVIGAPNKTH MDEILLENLP YAMGIIFNET FSYKLIFFQG YNSPLWK
Target Information
The ATP-binding cassette (ABC) superfamily consists of transmembrane proteins that mediate energy-dependent transport of various substrates across membranes.
ABCA6 is a 1,617 amino acid protein belonging to the ABC transporter family. It is up-regulated during monocyte differentiation into macrophages, suggesting a role in macrophage lipid homeostasis.
ABCA6 contains two ABC transporter domains and is expressed as three isoforms produced by alternative splicing.
Highest expression levels are found in adult liver, with significant expression in adult tissues and fetal lung, kidney, and liver.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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