Thermo Fisher Scientific CD36 Monoclonal Antibody (TR9), PE

Thermo Fisher Scientific CD36 Monoclonal Antibody (TR9), PE

Applications

• Flow Cytometry (Flow): 20 µL / 1×10⁶ cells

Product Specifications

Additional Formats

• Unconjugated
• APC
• FITC
• Request custom conjugation

Product Specific Information

This antibody reacts with an extracellular epitope of CD36 (GPIIIb), an 85 kDa integral membrane glycoprotein expressed on platelets, macrophages, endothelial cells, early erythroid cells, and megakaryocytes.
The TR9 clone cross-blocks binding of FITC-labeled antibody OKM5.
Anti-CD36 antibodies inhibit adhesive functions such as adherence of infected erythrocytes to target cells.

Target Information

CD36 (scavenger receptor class B member 3) is expressed on macrophages, platelets, adipocytes, and other cell types.
It plays a key role in lipid metabolism, inflammation, and atherosclerosis, mediating recognition and uptake of oxidized LDL, long-chain fatty acids, and apoptotic cells.
CD36 also serves as a receptor for thrombospondin and mediates cytoadherence of Plasmodium falciparum-infected erythrocytes.
Mutations may cause platelet glycoprotein deficiency and are associated with coronary heart disease.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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