Thermo Fisher Scientific MAGI3 Polyclonal Antibody
MAGI3 단백질을 인식하는 토끼 폴리클로날 항체로, WB 및 IHC 분석에 사용 가능. 합성 펩타이드 항원을 기반으로 제작되어 높은 특이성을 제공. 동결건조 형태로 제공되며, 4°C 단기 또는 -20°C 장기 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:200–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:200–1:2,000 | - |
| Miscellaneous PubMed (Misc) | – | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from amino acid region 1310–1360 of mouse MAGI3 conjugated to an immunogenic carrier protein. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: MAGI3.
Target Information
Membrane-associated guanylate kinase with inverted orientation (MAGI3) is a 130 kDa guanylate kinase belonging to a family of multi-PDZ domain-containing guanylate kinases. These proteins are localized to epithelial cell tight junctions.
MAGI3 and PTEN/MMAC cooperate to modulate the kinase activity of AKT/protein kinase B (PKB). MAGI3 positions the PTEN/MMAC phosphatase to subcellular locations involved in the regulation of cell proliferation and survival.
MAGI3 and related proteins include an N-terminal guanylate kinase domain, a WW domain (containing two conserved tryptophan residues), and five PDZ domains.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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