Thermo Fisher Scientific GSK3B Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:3,000

Immunocytochemistry (ICC/IF)

• Tested Dilution: Assay-dependent

Product Specifications

Product Specific Information

Store as a concentrated solution. Centrifuge briefly prior to opening vial.
For short-term storage (1–2 weeks), store at 4°C.
For long-term storage, aliquot and store at -20°C or below.
Avoid multiple freeze-thaw cycles.

Target Information

GSK3B is a proline-directed serine/threonine protein kinase involved in energy metabolism, neuronal cell development, and body pattern formation.
It acts as a negative regulator of glucose homeostasis and participates in processes such as inflammation, ER stress, mitochondrial dysfunction, and apoptosis.
GSK3B is a key component of the Wnt/β-catenin signaling pathway, mediating β-catenin degradation and inhibiting Wnt signaling.
It is also associated with Hedgehog, Notch, and insulin signaling pathways.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.