Thermo Fisher Scientific MCM-BP Polyclonal Antibody
Thermo Fisher Scientific의 MCM-BP Polyclonal Antibody는 인간 MCMBP 단백질에 특이적인 rabbit IgG 항체입니다. Western blot 및 immunoprecipitation에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 4°C에서 보관합니다.
- 판매단위
- pk
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Applications
- Western Blot (WB): 1:2,000–1:10,000
- Immunoprecipitation (IP): 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 150 and 200 of human Minichromosome Maintenance Complex Binding Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
MEK1 (Mitogen activated protein kinase kinase 1) catalyzes the concomitant phosphorylation of threonine and tyrosine residues in a Thr-Glu-Tyr sequence located in MAP kinases.
MEK1 activates ERK1 and ERK2 MAP kinases.
MEK2 (MAPKK2) is a member of a family of tyrosine/threonine protein kinases that activate ERK1/2 and MAPK enzymes by phosphorylating residues within the TEY motif in the activation loop.
MEK1 and MEK2 are activated by dual phosphorylation on serine 218 and 222 in the activation loop.
Threonine 292 of MEK1 is phosphorylated by ERK2, serving as a negative feedback loop that suppresses MEK1 activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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