Thermo Fisher Scientific F11 Monoclonal Antibody (2H8)
인간 F11 단백질을 인식하는 마우스 모노클로날 항체. Western blot, ELISA, IP에 사용 가능. GST 태그 결합 재조합 단백질로부터 유래한 면역원. PBS 용액 형태, 보존제 무첨가, -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 10 ng/mL |
| Immunoprecipitation (IP) | 1–5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2H8 |
| Immunogen | F11 (NP_000119, 286–385 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
SIPVFCHSSF YHDTDFLGEE LDIVAAKSHE ACQKLCTNAV RCQFFTYTPA QASCNEGKGK CYLKLSSNGS PTKILHGRGG ISGYTLRLCK MDNECTTKIK
Target Information
This gene encodes coagulation factor XI of the blood coagulation cascade. It is present in plasma as a zymogen, existing as a homodimer of two identical polypeptide chains linked by disulfide bonds. Activation by factor XIIa cleaves internal peptide bonds, producing factor XIa, a serine protease composed of two heavy and two light chains. Activated factor XI triggers the intrinsic pathway of blood coagulation by activating factor IX. Defects in this factor can lead to Rosenthal syndrome, a coagulation abnormality.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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