Thermo Fisher Scientific Phospho-kappa-Opioid Receptor (Ser356, Thr357) Polyclonal Antibody
인산화된 kappa-Opioid Receptor(Ser356, Thr357)를 특이적으로 인식하는 Rabbit Polyclonal Antibody. Western blot에 적합하며, Human, Mouse, Rat에 반응합니다. 항원 친화 크로마토그래피로 정제되었고, 1 mg/mL 농도의 액상 형태로 제공됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human KOP around the phosphorylation site of Ser356/Thr357 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
This gene encodes an opioid receptor, a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands and various synthetic opioids. Ligand binding inhibits adenylate cyclase activity and neurotransmitter release. This receptor is involved in pain perception and mediates the hypolocomotor, analgesic, and aversive actions of synthetic opioids. Variations in this gene are associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been identified. A recent study also suggested translational readthrough resulting in a C-terminally extended isoform.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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