Thermo Fisher Scientific CD19 Polyclonal Antibody
Rabbit polyclonal antibody targeting human CD19. Validated for Western blot with 1:1,000 dilution. Purified via Protein A and antigen affinity chromatography. Supplied as liquid in PBS with sodium azide. For research use only.
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Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide corresponding to amino acids 393–421 of the C-terminal region of human CD19 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.45 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C for short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2072932 |
Target Information
CD19 is a member of the immunoglobulin superfamily with two Ig-like domains. It is expressed on 100% of peripheral B cells defined by kappa or lambda light chain expression. CD19 is also observed on certain myeloid leukemia cells, particularly those of monocytic lineage. It serves as a key regulator of B cell activation and proliferation, acting as a signal-amplifying coreceptor for the B cell receptor (BCR). Mutations in the CD19 gene can cause hypogammaglobulinemia, while overexpression can lead to B cell hyperactivity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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