Thermo Fisher Scientific CD307e (FcRL5) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.1 µg/mL

-

Flow Cytometry (Flow)

0.25 µg per million cells

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Product Specifications

Species Reactivity

Human

Published species

Not Applicable

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Mouse myeloma cell line NS0-derived recombinant human FCRL5/FcRH5 Gln16-Arg844 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:FcRL5,uniProtId:Q96RD9-1,ncbiNodeId:9606,antigenRange:16-844,antigenLength:977,antigenImageFileName:PA5-48003_FcRL5_Q96RD9-1_Goat.svg,antigenImageFileNamePDP:PA5-48003_FcRL5_Q96RD9-1_Goat_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2605924

Product Specific Information

In direct ELISAs, approximately 10% cross-reactivity with recombinant human (rh) IRTA3, rhIRTA4, and rhIRTA5 is observed and less than 5% cross-reactivity with rhIRTA1 is observed.

Reconstitute at 0.2 mg/mL in sterile PBS.

Target Information

Fc receptor homologs (FcRH5), also known as IRTA2 proteins, are transmembrane proteins with sequence homology to classical Fc receptor families. FcRH5 function as activating or inhibitory receptors on discrete B cell populations and are involved in B-cell development and differentiation in peripheral lymphoid organs. FcRH5 expression is deregulated in multiple myeloma and Burkitt lymphoma cell lines with 1q21 abnormalities. FcRH5 may play a critical role for the pathogenesis of B-cell lymphoma.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.