Thermo Fisher Scientific PDGF-B Polyclonal Antibody
PDGF-B 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC 등 다양한 응용에 적합. Human 및 Mouse 반응성 확인. 항원 친화 크로마토그래피로 정제되었으며, 0.9 mg/mL 농도의 액상 형태로 제공. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL | - |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:150 | - |
| Immunocytochemistry (ICC/IF) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide conjugated to KLH derived from within residues 100–200 of Human PDGF B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.9 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10980265 |
Product Specific Information
This antibody is predicted to react with rat and cow based on sequence homology.
Store antibody at 4ºC for 1–2 weeks. For long-term storage, store at -20ºC.
Target Information
This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit B, which can homodimerize or heterodimerize with PDGF subunit A. These proteins activate PDGF receptor tyrosine kinases involved in diverse developmental processes.
Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, involving this gene and collagen type I alpha 1, are linked to dermatofibrosarcoma protuberans, a rare skin tumor.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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