Thermo Fisher Scientific GPX4 Recombinant Rabbit Monoclonal Antibody (ARC0558)
GPX4 단백질을 인식하는 토끼 단클론 항체로 Western blot, ICC/IF, ELISA에 적합. 인간, 생쥐, 랫트에 반응하며 HEK293 세포에서 발현된 재조합 항체. 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:6,000 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:200–1:800 | - |
| ELISA | 1 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0558 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 1–100 of human GPX4 (P36969) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.69 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2848994 |
Product Specific Information
Immunogen sequence:
MSLGRLCRLL KPALLCGALA APGLAGTMCA SRDDWRCARS MHEFSAKDID GHMVNLDKYR GFVCIVTNVA SQUGKTEVNY TQLVDLHARY AECGLRILAF
Target Information
Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione, functioning in the protection of cells against oxidative damage. Human plasma glutathione peroxidase is a selenium-containing enzyme where the UGA codon encodes selenocysteine. In rats, alternative splicing and transcription initiation produce proteins localized to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists; the cleavage sites of mitochondrial and nuclear transit peptides require further experimental verification.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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