Thermo Fisher Scientific H2BK12ac Polyclonal Antibody
H2BK12ac에 특이적인 Rabbit Polyclonal Antibody로, 인간·마우스·랫트 시료에 반응합니다. Western blot, IHC, ICC, ELISA, ChIP 등 다양한 응용에 적합하며, 고순도 Affinity Chromatography 정제 제품입니다. 액상 형태로 -20°C 보관 권장.
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Thermo Fisher Scientific H2BK12ac Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
| ChIP assay (ChIP) | 5 µg antibody for 5–10 µg of Chromatin |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic acetylated peptide around K12 of human Histone H2B (NP_003519.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.51 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855225 |
Product Specific Information
Immunogen sequence: APKKG
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). These nucleosomes further compact DNA into chromatin, limiting DNA accessibility to cellular machineries which require DNA as a template.
Histones play central roles in transcription regulation, DNA repair, replication, and chromosomal stability. H2B also exhibits broad antibacterial activity.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
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