Thermo Fisher Scientific AgRP Polyclonal Antibody

Applications

Immunohistochemistry (Frozen) (IHC (F))

• Tested Dilution: 1.7–5 µg/mL

Product Specifications

Product Specific Information

• In direct ELISAs, less than 25% cross-reactivity with recombinant human AgRP is observed.
• Reconstitute at 0.2 mg/mL in sterile PBS.

Target Information

Agouti-related protein (AgRP), also known as agouti-related peptide, is a neuropeptide produced in the brain by AgRP/NPY neurons. In humans, the AgRP peptide is encoded by the AGRP gene, which acts as an antagonist of melanocortin-3 and melanocortin-4 receptors.
It regulates hypothalamic control of feeding behavior through melanocortin receptor and/or intracellular calcium signaling, playing a critical role in weight homeostasis. Mutations in this gene have been linked to late-onset obesity.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.