Thermo Fisher Scientific AgRP Polyclonal Antibody
마우스 AgRP 단백질을 인식하는 염소 폴리클로날 항체로, IHC(F) 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 보존제가 없는 동결건조 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
Immunohistochemistry (Frozen) (IHC (F))
- Tested Dilution: 1.7–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Sf21-derived recombinant mouse AgRP/ART (Val25–Thr131) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS with 5% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2608453 |
Product Specific Information
- In direct ELISAs, less than 25% cross-reactivity with recombinant human AgRP is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
Agouti-related protein (AgRP), also known as agouti-related peptide, is a neuropeptide produced in the brain by AgRP/NPY neurons. In humans, the AgRP peptide is encoded by the AGRP gene, which acts as an antagonist of melanocortin-3 and melanocortin-4 receptors.
It regulates hypothalamic control of feeding behavior through melanocortin receptor and/or intracellular calcium signaling, playing a critical role in weight homeostasis. Mutations in this gene have been linked to late-onset obesity.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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