Thermo Fisher Scientific Phospho-PAK2 (Ser192) Polyclonal Antibody
Rabbit polyclonal antibody recognizing phosphorylated PAK2 (Ser192). Validated for Western blot applications. Targets human PAK2 involved in cytoskeleton regulation and cell signaling. Supplied as liquid, 1 mg/mL, stored at −20 °C.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide derived from human PAK2 around Ser192 (T-K-SP-I-Y) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | −20 °C |
| Shipping Conditions | Wet ice |
| RRID | AB_2556300 |
Target Information
PAK2 (serine/threonine-protein kinase PAK2) is a serine/threonine kinase involved in multiple signaling pathways, including cytoskeleton regulation, cell motility, cell cycle progression, apoptosis, and proliferation. It functions downstream of the small GTPases CDC42 and RAC1. Activation by CDC42 and RAC1 induces conformational changes and autophosphorylation on serine/threonine residues. Full-length PAK2 promotes cell survival and growth. PAK proteins are key effectors linking Rho GTPases to cytoskeletal reorganization and nuclear signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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