Thermo Fisher Scientific MC1R Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 200-317 of human MC1 Receptor (NP_0023774) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MC1R,uniProtId:Q01726-1,ncbiNodeId:9606,antigenRange:200-317,antigenLength:317,antigenImageFileName:PA5-89029_MC1R_Q01726-1_Rabbit.svg,antigenImageFileNamePDP:PA5-89029_MC1R_Q01726-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.69 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2805308

Product Specific Information

Immunogen sequence: LVLMAVLYVH MLARACQHAQ GIARLHKRQR PVHQGFGLKG AVTLTILLGI FFLCWGPFFL HLTLIVLCPE HPTCGCIFKN FNLFLALIIC NAIIDPLIYA FHSQELRRTL KEVLTCSW; Positive Samples: HeLa, Mouse heart, Rat heart; Cellular Location: Cell membrane, Multi-pass membrane protein

Target Information

MC1R, a Melanocortin Receptor, mediates the effects of melanocyte-stimulating hormone (MSH) and adrenocorticotropic hormone (ACTH). MSH and its receptor, MC1R, are key regulators of melanogenesis. They control the relative proportions of red pheomelanin and black photoprotective eumelanin in the skin by increasing the production of eumelanin. Non-functional, truncated forms of the receptor lead to lighter coat color in animals. In contrast, constitutively active receptors lead to darker color.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.