Thermo Fisher Scientific SP3/SP4 Polyclonal Antibody
Human SP3/SP4 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF 등 다양한 응용에 적합. 고순도 Affinity chromatography 정제 제품으로, PBS/glycerol buffer에 보관. 연구용으로만 사용 가능.
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- PA599719
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- pk
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SP3 (Accession Q02447), corresponding to amino acid residues R639–R689. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818652 |
Product Specific Information
Antibody detects endogenous levels of total Sp3/4.
Target Information
This gene belongs to a family of Sp1-related genes that encode transcription factors regulating transcription by binding to consensus GC- and GT-box regulatory elements. The protein contains a zinc finger DNA-binding domain and several transactivation domains, functioning as a bifunctional transcription factor that can stimulate or repress transcription of numerous genes. Transcript variants encoding different isoforms have been described, including one initiating translation from a non-AUG (AUA) start codon. Additional isoforms may arise from alternate downstream translation initiation sites, and a related pseudogene has been identified on chromosome 13.
[Provided by RefSeq, Feb 2010]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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