Thermo Fisher Scientific DOK4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human DOK4. Recombinant protein control fragment (Product #RP-101658). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DOK4,uniProtId:Q8TEW6-1,ncbiNodeId:9606,antigenRange:40-98,antigenLength:326,antigenImageFileName:PA5-63190_DOK4_Q8TEW6-1_Rabbit.svg,antigenImageFileNamePDP:PA5-63190_DOK4_Q8TEW6-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2640745

Product Specific Information

Immunogen sequence: QRLEKYPDEK SVCLRGCPKV TEISNVKCVT RLPKETKRQA VAIIFTDDSA RTFTCDSEL

Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

Target Information

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells. [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.