Thermo Fisher Scientific DOK4 Polyclonal Antibody
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Applications
Tested Dilution
Publications
Immunohistochemistry (Paraffin) (IHC (P))
1:500-1:1,000
Immunocytochemistry (ICC/IF)
0.25-2 µg/mL
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit / IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human DOK4. Recombinant protein control fragment (Product #RP-101658). if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
DOK4,
uniProtId:
Q8TEW6-1,
ncbiNodeId:
9606,
antigenRange:
40-98,
antigenLength:
326,
antigenImageFileName:
PA5-63190_DOK4_Q8TEW6-1_Rabbit.svg,
antigenImageFileNamePDP:
PA5-63190_DOK4_Q8TEW6-1_Rabbit_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2640745
Product Specific Information
Immunogen sequence: QRLEKYPDEK SVCLRGCPKV TEISNVKCVT RLPKETKRQA VAIIFTDDSA RTFTCDSEL
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
Target Information
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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