Thermo Fisher Scientific COMT Monoclonal Antibody (630CT1.7.1)
인간 COMT 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot에 사용 가능. KLH 결합 합성 펩타이드(37–65 aa)로 면역화. 비결합형 액상 형태이며, 단기 4°C 보관 및 장기 -20°C 보관 권장. 연구용으로만 사용.
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Thermo Fisher Scientific COMT Monoclonal Antibody (630CT1.7.1)
Applications
- Western Blot (WB)
Tested Dilution: 1:100–1:400
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 630CT1.7.1 |
| Immunogen | KLH conjugated synthetic peptide between 37–65 amino acids from the N-terminal region of human COMT |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2897538 |
Target Information
Catechol-O-methyltransferase (COMT) catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including dopamine, epinephrine, and norepinephrine. This O-methylation is a major degradative pathway for catecholamine neurotransmitters. COMT also plays an important role in the metabolism of catechol drugs used for hypertension, asthma, and Parkinson’s disease.
COMT exists in two forms: soluble (S-COMT) and membrane-bound (MB-COMT), differing at their N-termini. Several transcript variants are generated via alternative translation initiation sites and promoters.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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